Academic Career and Research Areas
The research work of Professor Antes (b. 1969) is in the interdisciplinary field between theoretic biochemistry and bioinformatics. Her particular interest lies in the development of new methods to research structural-functional relationships in biomolecules and their implementation in the computer programs primarily used in pharmaceutical research (developing active ingredients) and biotechnology (enzymatic catalysis). In addition to this, her research group focuses on medically relevant questions in the fields of immunology (immunotherapy) and virology (development of viral resistance).
After studying chemistry at the Universities of Tübingen and Marburg, Professor Antes completed her PhD in Zurich in theoretical chemistry. Prior to working as a professor at TUM, she held research positions at the University of Pennsylvania, the University of California, Berkeley, and the Max Planck Institute for Informatics, Saarbrücken, where she acquired her postdoctoral teaching qualification (habilitation) in bioinformatics (at the Department for Informatics and Mathematics).
Antes I: “Dyna Dock: A new molecular dynamics based algorithm for protein-peptide docking including receptor flexibility”. Proteins. 2010; 78: 1084-1104.Abstract
Antes I, Siu SWI, Lengauer T: “DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations”. Bioinformatics. 2006; 22: 16-24.Abstract
Antes I, Wang H, Chandler D, Oster G: "The unbinding of ATP from F1-ATPase."
Biophysical Journal. 2003; 85(2): 695-706.
Antes I, Thiel W: “Adjusted Connection Atoms for Combined Quantum Mechanical and Molecular Mechanical Methods”. Journal of Physical Chemistry A. 1999; 103: 9290-9295.Abstract
Antes I, Frenking G: “Structure and Bonding of the Transition Metal Methyl and Phenyl Compounds MCH3, MC6H5 (M = Cu, Ag, Au) and M(CH3)2, M(C6H5)2 (M = Zn, Cd, Hg)”. Organometallics. 1995; 14(9): 4263-4268.Abstract