Prof. Dr. Thomas Korn
Academic Career and Research Areas
Professor Korn is a neuroimmunologist whose research concentrates on T-cell autoimmune reactions in the central nervous system. His work explores the differentiation and plasticity of autoreactive effector T-cells and regulatory T-cells in multiple sclerosis model systems. His aim is to apply the principles of specific immune modulation for therapeutic interventions in autoimmune diseases and chronic inflammation by identifying and validating molecular switches for T-cell differentiation.
Prof. Korn (b. 1972) studied medicine in Würzburg and London and obtained his doctorate in cell biology at the University of Würzburg. After specialist training in neurology in Würzburg and Homburg, he obtained a German Research Foundation (DFG) research grant to spend 3 years working on basic immunological T-cell projects at Harvard Medical School in Boston. After completing his postdoctoral studies in neurology while working as a senior physician in the Neurology Clinic at TUM’s rechts der Isar clinic, he was appointed associate professor of experimental neuroimmunology at TUM in 2010.
- Curriculum Vitae
- Heinrich-Pette-Preis der Deutschen Gesellschaft für Neurologie (2010)
- Heisenberg-Stipendium der Deutschen Forschungsgemeinschaft (2008)
- Sobek Nachwuchspreis (2008)
- Helmut-Bauer-Preis für Multiple Sklerose Forschung (2007)
Petermann F, Rothhammer V, Claussen MC, Haas JD, Blanco LR, Heink S, Prinz I, Hemmer B, Kuchroo VK, Oukka M, Korn T: “γδ T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism”. Immunity. 2010; 33(3): 351-63.Abstract
Korn T, Bettelli E, Oukka M, Kuchroo VK: “IL-17 and Th17 Cells”. Annu Rev Immunol. 2009; 27: 485-517.Abstract
Korn T, Bettelli E, Gao W, Awasthi A, Jäger A, Strom TB, Oukka M, Kuchroo VK: “IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells”. Nature. 2007; 448(7152): 484-7.Abstract
Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Bäckström BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK: “Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation”. Nat Med. 2007; 13(4): 423-31.Abstract
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK: “Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells”. Nature. 2006; 441(7090): 235-8.Abstract