Prof. Dr. Christian Peschel
Academic Career and Research Areas
Professor Peschel (b. 1950) conducts research in the field of hematology and tumor biology. The goal of his research is to develop the basis for individualized, goal-oriented treatment plans for patients with leukemia and cancer through a better understanding of the cell biological and molecular basis of tumor disease. The disease models at the centre of this fundamental and translational research include acute and chronic leukemia and tumor disease of the lymphatic system (non-Hodgkin’s lymphoma). Professor Peschel studied medicine at the University of Innsbruck where he acquired his postdoctoral teaching qualification (habilitation) in 1989. From 1985 -1987 he worked as a research fellow in the USA at William E. Paul, Laboratory of Immunology, at the National Institutes of Health. From 1990 - 1997 he was the senior physician (C3 Professor) at the University Clinic in Mainz. In 1997 he was appointed to the newly established chair within the TUM School of Medicine specializing in hematology and internal oncology.
Key Publications
Renstrom J, Istvanffy R, Gauthier K, Shimono A, Mages J, Jardon-Alvarez A, Kroger M, Schiemann M, Busch DH, Esposito I, Lang R, Peschel C, Oostendorp RA: "Secreted frizzled-related protein 1 extrinsically regulates cycling activity and maintenance of hematopoietic stem cells". Cell Stem Cell. 2009; 5: 157-167.
AbstractBassermann F, von Klitzing C, Munch S, Bai RY, Kawaguchi H, Morris SW, Peschel C, Duyster J: "NIPA defines an SCF-type mammalian E3 ligase that regulates mitotic entry". Cell. 2005; 122: 45-57.
AbstractRingshausen I, Schneller F, Bogner C, Hipp S, Duyster J, Peschel C, Decker T: "Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with Proteinkinase C{delta}". Blood. 2002; 100: 3741-3748.
AbstractBai RY, Ouyang T, Hahn S, Peschel C, Duyster J: "Smif, a novel Smad4-interacting Protein acts as a crucial transcriptional Co-Activator In TGF-b Signalling". Nature Cell Biology. 2002; 4: 181-19.
AbstractDecker T, Schneller F, Sparwasser T, Tretter T, Lipford GB, Wagner H, Peschel C: "Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production and an immungenic phenotype in chronic lymphocytic leukemia B cells". Blood. 2000; 95: 999-1006.
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