Prof. Dr. Heiko Lickert
Diabetes and Regeneration Research / Beta-Cell Biology
Academic Career and Research Areas
Prof. Lickert is a full professor and holds the Chair of ß-Cell Biology at TUM School of Medicine. He is also director of the Institute of Diabetes and Regeneration Research (IDR) and adjunct professor at the Institute of Stem Cell Research (ISF) at Helmholtz Zentrum München. He is on the executive committee of the Helmholtz Diabetes Center (HDC) and TUMCells GMP Facility and on the research coordination board of the German Center for Diabetes Research (DZD).
He obtained his PhD from the University of Freiburg and Max Planck Institute in Freiburg. His postdoctoral studies were carried out at Mount Sinai Hospital, Toronto, Canada. He is an expert on organ development and tissue homeostasis with emphasis on endocrine lineage formation in the gut and pancreas, insulin-producing ß-cell development, regeneration and replacement, as well as metabolic signaling and stem cell-based drug screening. His work has been funded by the European Research Council (ERC), a prestigious Emmy-Noether fellowship of the German Research Foundation (DFG), the Ministry of Education and Research (BMBF), the Alexander von Humboldt Foundation, the Helmholtz Association and the European Union.
- Paula und Richard von Hertwig Prize for Interdisciplinary Cooperation (2011)
- ERC Grant (2009)
- Emmy Noether Fellow (2005)
- Otto-Hahn-Medal, Max Planck Society (2003)
- Hans-Spemann Prize, University of Freiburg (2002)
Key Publications (alle Publikationen)
Bader E et al: "Identification of proliferative and mature β-cells in the islets of Langerhans". Nature. 2016; 535(7612): 430-434.https://www.ncbi.nlm.nih.gov/pubmed/27398620
Hoppe PS et al.: "Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios". Nature. 2016; 535: 299-302.https://www.nature.com/articles/nature18320
Roscioni S, Migliorini A, Gegg M, Lickert H: "Impact of islet architecture on β-cell heterogeneity, plasticity and function". Nat. Rev. Endocrinol. 2016; 12(12): 695-709.https://www.ncbi.nlm.nih.gov/pubmed/27585958
Nikoletopoulou V et al: "Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not". Nature. 2010; 467(7311): 59-63.https://www.ncbi.nlm.nih.gov/pubmed/20811452
Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG.: "Baf60c is essential for function of BAF chromatin remodelling complexes in heart development". Nature. 2004; 432(7013): 107-112.https://www.ncbi.nlm.nih.gov/pubmed/15525990