Prof. Dr. Heiko Witt

Associate Professor

Paediatric Nutritional Medicine

Contact Details

Business card at TUMonline

Academic Career and Research Areas

Professor Witt (b. 1966) conducts research on the molecular causes of gastroenterological disease in children and young adults. The focus is on the identification of genes causing disease that predispose people to the development of pancreatic diseases such as chronic pancreatitis. His research interests also include the genetics of chronic inflammatory disease of the bowel, various liver disease and fructose malabsorption.

After studying medicine and earning a PhD (1998) at the Humboldt University of Berlin, Professor Witt acquired his postdoctoral teaching qualification (habilitation) at the Charité (2004). In 2008 he assumed a professorship position funded by the Else Kröner-Fresenius Foundation (EKFS) at TUM. Professor Witt is a member of the German Society of Pediatrics and Adolescent Medicine (Deutsche Gesellschaft für Kinder- und Jugendmedizin - DGKJ), the German Society of Digestive and Metabolic Disorders (Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten – DGVS), the Society of Paediatric Gastroenterology and Nutrition (Gesellschaft für Pädiatrische Gastroenterologie und Ernährung – GPGE), the European Pancreas Club (EPC), the International Association of Pancreatology (IAP) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN).


  • Dr. Norbert Henning-Preis für Gastroenterologie (2003)
  • Ehrenmitglied der Medizinischen und Naturwissenschaftlichen Gesellschaft der Universität Parma (2003)
  • Forschungspreis der Charité (2000)

Key Publications

Rosendahl J, Witt H, Szmola R, et al.: “Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis”. Nature Genet. 2008; 40: 78-82.

Witt H, Sahin-Tóth M, Landt O, et al.: “A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis”. Nature Genet. 2006; 38: 668-673.

Witt H, Luck W, Becker M, et al.: “Mutation in the SPINK 1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis”. JAMA. 2001; 285: 2716-2717.

Witt H, Luck W, Hennies HC, et al.: “Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis”. Nature Genet. 2000; 25: 213-216.