Persönlicher Status und Werkzeuge

Prof. Dr. Ellen D. Renner

Assistant Professor

Translational Immunology
in Environmental Health

Academic Career and Research Areas

Professor Renner`s research focuses on the interaction of human immunity with the environment. As a physician-scientist her overall goal is disease prevention and to improve patient care. Professor Renner focuses on rare primary immunodeficiencies as human model diseases of common afflictions such as allergic diseases, including atopic eczema.
She went to the School of Medicine at LMU Munich, specialized in pediatrics at Dr. von Hauner Children`s Hospital, LMU. After research activity at the Hôpital Necker, Paris and at University of Washington, Seattle she returned to Dr. von Hauner Children`s Hospital, where she directed the diagnostic laboratory of immunology and established an independent and internationally connected research group receiving several research grants including DFG funding. In 2016 she joined the faculty of the TUM Medical School at UNIKA-T (University Centre for Health Care Sciences at Klinikum Augsburg). She serves also as study coordinator at the Christine Kühne Foundation, Hochgebirgsklinik Davos. Her research group is located at HelmholtzZentrum München and UNIKA-T.

    Awards

    • International travel award, AAAAI New Orleans (US) (2010)
    • American Academy of Allergy, Asthma and Immunology’s Strategic Training in Allergy Research (ST*AR) Award 2007, San Diego (US) (2007)
    • CIS Primary Immunodeficiency Summer School, Miami (US) (2006)
    • ESID Primary Immunodeficiency Summer School, Algarve (PT) (2003)
    • Research Award Infectious Diseases, Merck (GER) (2003)

    Key Publications

    Boos AC, Hagl B, Schlesinger A, Halm BE, Ballenberger N, Pinarci M, Heinz V, Kreilinger D, Spielberger BD, Schimke-Marques LF, Sawalle-Belohradsky J, Belohradsky BH, Przybilla B, Schaub B, Wollenberg A, Renner ED: „Atopic Dermatitis, STAT3- and DOCK8-Hyper-IgE Syndromes Differ in IgE-based Sensitization Pattern“. Allergy. 2014; 69(7): 943-53.

    Abstract

    Hill DA, Siracusa MC, Abt MC, Kim BS, Kobuley D, Kubo M, Kambayashi T, LaRosa DF, Renner ED, Orange JS, Bushman FD & Artis D: „Commensal bacterial–derived signals regulate basophil hematopoiesis and allergic inflammation”. Nature Medicine. 2012; 18(4): 538-46.

    Abstract

    Renner ED, Rylaarsdam S, Anover-Sombke S, Rack AL, Reichenbach J, Carey JC, Zhu Q, Jansson AF, Barboza J, Schimke LF, Leppert MF, Getz MM, Seger RA, Hill HR, Belohradsky BH, Torgerson TR, Ochs HD: „Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome”. J Allergy Clin Immunol. 2008; 122(1): 181-187.

    Abstract

    Renner ED, Torgerson TR, Rylaarsdam S, Anover-Sombke S, Golob K, LaFlam T, Zhu Q, Ochs HD: “STAT3 mutation in the original patient with Job's syndrome”. N Engl J Med. 2007; 357(16): 1667-8.

    Abstract

    Renner ED, Puck, JM, Holland, SM, Schmitt M, Weiss, M, Frosch M, Bergmann, M, Davis, J, Belohradsky, BH, Grimbacher, B: „Autosomal recessive hyperimmunoglobulin E syndrome: a distinct disease entity“. J. Pediatr. 2004; 144: 93-9.

    Abstract