Academic Career and Research Areas
Professor Gänsbacher (b. 1948) conducts research in the field of gene transfer technologies with the goal of developing new strategies for the treatment of cancer and genetically determined disease.
After completing a fellowship in internal medicine, allergy / immunology and hematology / oncology at the University of Pennsylvania and at the Memorial Sloan-Kettering Cancer Center, Professor Gänsbacher was a professor on the faculty of the Memorial Sloan-Kettering Cancer Center in New York for eleven years. Since 1996 he has held a professor position in experimental oncology and treatment research and been director of the institute of the same name at Klinikum rechts der Isar. He is the author of over 130 scientific articles and several books.
- President of the European Society of Gene Therapy (ESGT) (2000-2004)
- CaP CURE Research Award (1994)
- Prize from the Degussa-Foundation (1993)
Brill TH, Kübler HR, Pohla H, Buchner A, Fend F, Schuster T, van Randenborgh R, Paul R, Kummer T, Plank C, Eisele B, Breul J, Hartung R, Schendel DJ, Gansbacher B: "Therapeutic Vaccination with an Interleukin-2–Interferon-γ-Secreting Allogeneic Tumor Vaccine in Patients with Progressive Castration-Resistant Prostate Cancer: A Phase I/II Trial". Hum. Gene. Ther. 2009; 20(12): 1641-51.Abstract
Gansbacher B, Houghton A, Livingston P, Minasian L, Rosenthal F, Gilboa E, Oettgen H, Steffens T, Young Yang S, Wong G: "A pilot study of immunization with HLA A2 matched allogeneic melanoma cells that secrete interleukin-2 in patients with metastatic melanoma". Hum. Gene. Ther. 1992; 3(6): 677-90.Abstract
Gansbacher B, Motzer R, Houghton A, Bander N, Minasian L, Gastl G, Rosenthal F, Gilboa E, Scheinfeld J, Young Yang S, Wong G, Golde D, Reuter V, Livingston P, Bosl G, Nanus D, Fair WR: "A pilot study of immunization with interleukin-2 secreting allogeneic HLA-A2 matched renal cell carcinoma cells in patients with advanced renal cell carcinoma". Hum. Gene. Ther. 1992; 3(6): 691-703.Abstract
Gansbacher B, Zier K, Cronin K, Hantzopoulos PA, Bouchard B, Houghton A, Gilboa E, Golde D: "Retroviral gene transfer induced constitutive expression of interleukin-2 or interferon-gamma in irradiated human melanoma cells". Blood. 1992; 80: 2817-2825.Abstract
Gansbacher B, Zier K, Daniels B, Cronin K, Bannerji R, Gilboa E: "Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity" J. Exp. Med. 1990; 172(4): 121.Abstract