Academic Career and Research Areas
Professor Herzen (*1980) conducts research on biomedical imaging. The main focus of her research is the development of new methods in X-ray computed tomography based on spectral detection and X-ray phase contrast for medicine and biology. She uses both, highly-brilliant synchrotron radiation and standard polychromatic X-ray tubes for her research. Besides the improvement of image quality, another major objective of Herzen’s work is quantitative imaging – a procedure which allows for extracting element-specific measures from X-ray images.
Professor Herzen studied physics at the University of Hamburg (2006) and obtained her doctorate – which included a research stay at the Paul Scherrer Institute (Switzerland, 2008) – from the Helmholtz-Zentrum Geesthacht in 2010. She then worked as a post-doctoral researcher at TUM (2010 & 2014) and at the synchrotron source PETRA III (Hamburg, 2012) and held a position as interim professor at TU Dortmund (2015) before being appointed as Assistant Professor for Biomedical Imaging Physics at TUM in 2018.
Key Publications (all publications)
Busse M, Müller M, Kimm MA, Ferstl S, Allner S, Achterhold K, Herzen J, Pfeiffer F: "Three-dimensional virtual histology enabled through cytoplasm-specific X-ray stain for microscopic and nanoscopic computed tomography". Proceedings of the National Academy of Sciences. 2018; 115(10): 2293-2298.Abstract
Gromann LB, De Marco F, Willer K, Noël PB, Scherer K, Renger B, Gleich B, Achterhold K, Fingerle AA, Muenzel D, Auweter S, Hellbach K, Reiser M, Baehr A, Dmochewitz M, Schroeter TJ, Koch FJ, Meyer P, Kunka D, Mohr J, Yaroshenko A, Maack H-I, Pralow T, van der Heijden H, Proksa R, Koehler T, Wieberneit N, Rindt K, Rummeny EJ, Pfeiffer F, Herzen J: "In-vivo X-ray Dark-Field Chest Radiography of a Pig". Nature Scientific Reports. 2017; 7: 4807.Abstract
Birnbacher L, Willner M, Velroyen A, Marschner M, Hipp A, Meiser J, Koch F, Schröter T, Kunka D, Mohr J, Pfeiffer F, Herzen J: "Experimental realisation of high-sensitivity laboratory X-ray grating-based phase-contrast computed tomography". Nature Scientific Reports. 2016; 6: 24022.Abstract
Schleede S, Meinel FG, Bech M, Herzen J, Achterhold K, Potdevin G, Malecki A, Adam-Neumair S, Thieme SF, Bamberg F, Nikolaou K, Bohla A, Yildirim AO, Loewen R, Gifford M, Ruth R, Eickelberg O, Reiser M, Pfeiffer F: "Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source". Proceedings of the National Academy of Sciences. 2012; 109(44): 17880-17885.Abstract
Herzen J, Donath T, Pfeiffer F, Bunk O, Padeste C, Beckmann F, Schreyer A, David C: "Quantitative phase-contrast tomography of a liquid phantom using a conventional x-ray tube source". Optics Express. 2009; 17(12): 10010-10018.Abstract