Prof. Dr.-Ing. Andreas Kremling


Systems biotechnology

Academic Career and Research Areas

Prof. Kremling (b. 1965) explores the theoretical and experimental aspects of biotechnology processes. He particularly aim at developing and analyzing meaningful mathematical models for optimal process design. In the focus are bacterial systems like Escherichia coli, Pseudomonas putida and Halomonas elongata. In a new project, he investigates mixed cultures with phototroph and heterotroph bacteria that produce bio-plastic.

After studying technical cybernetics in Stuttgart, he did his doctorate there in 2002. He completed his lecturer qualification at the University of Magdeburg in 2009. In 1998, he had commenced his research activities  in systems biology at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg. In 2010, he was appointed as an associate professor of system biotechnology at TUM.

Key Publications (alle Publikationen)

Löwe H, Hobmeier K, Moos M, Kremling A, Pflüger-Grau K: “Photoautotrophic production of polyhydroxyalkanoates in a synthetic mixed culture of Synechococcus elongatus cscB and Pseudomonas putida cscAB”. Biotechnology for Biofuels. 2017; 10: 190. 


Valderrama-Gomez MA, Kreitmayer D, Wolf S, Marin-Sanguino A, Kremling A: “Application of theoretical methods to increase succinate production in engineered strains”. Bioprocess and Biosystems Engineering. 2017; 40 (4): 479–497. 


Hahl SK, Kremling A: “A Comparison of Deterministic and Stochastic Modeling Approaches for Biochemical Reaction Systems: On Fixed Points, Means, and Modes”. Frontiers in Genetics. 2016; 7.


Kremling A, Geiselmann J, Ropers D, de Jong H: “Understanding carbon catabolite repression in Escherichia coli using quantitative models”. Trends in Microbiology. 2015; 23 (2): 99-109. 


Bettenbrock K, Fischer S, Kremling A, Jahreis K, Sauter T, Gilles, ED: “A quantitative approach to catabolite repression in Escherichia coli”. JBC. 2006; 281.