Prof. Dr. Eleftheria Zeggini
Academic Career and Research Areas
Prof. Zeggini works in the field of Translational Genomics. Her research leverages big biomedical data and aims to translate insights from genomics into mechanisms of disease development and progression, shortening the path to translation and empowering precision medicine. She develops and applies robust statistical and computational tools to integrate information gleaned from deep molecular, genomics epidemiological approaches to address important biomedical research challenges.
Prof. Zeggini obtained a BSc in Biochemistry at UMIST and a PhD in the Immunogenetics of Juvenile Arthritis at the University of Manchester. In 2004, she moved to the Wellcome Centre for Human Genetics in Oxford and in 2008 joined the Wellcome Sanger Institute Human Genetics Faculty. In 2018, she founded the Institute of Translational Genomics at the Helmholtz Zentrum München. In 2020, Prof. Zeggini was appointed to the TUM Liesel Beckmann Distinguished Professorship for Translational Genomics at TUM.
Awards
- Elected Member of Academia Europaea (2024)
- Elected Greek National Representative to the EMBL Council (2022)
- Elected ELLIS Fellow, ELLIS unit Munich, Germany (2021)
- Elected Member of EMBO (2021)
- Elected Fellow of the Academy of Medical Sciences, London, UK (2020)
Key Publications (all publications)
Hatzikotoulas K*, Southam L*, Stefansdottir L*, Boer CG*, McDonald ML*, …, Zeggini E: “Translational genomics of osteoarthritis in 1,962,069 individuals”. Nature. 2025; in press.
AbstractRayner NW, …, Zeggini E. Toward GDPR compliance with the Helmholtz Munich genotype imputation server. Nat Genet 2024, 56:2580-2581.
AbstractSuzuki K*, Hatzikotoulas K*, Southam L*, Taylor HJ*, Yin X*, Lorenz KM*, Mandla R*, ..., Voight BF*, Morris AP*, Zeggini E*. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature 2024, 627:347-357.
AbstractBoer CG*, Hatzikotoulas K*, Southam L*, ..., Zeggini E. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. Cell 2021, 184:4784-4818.e17.
AbstractZeggini E, et al. Translational Genomics and Precision Medicine: moving from the lab to clinic. Science 2019, 365: 1409-1413.
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