Dr. Chien-Yun Lee
Academic Career and Research Areas
Dr. Chien-Yun Lee studied Life Sciences at the National Chung Hsing University in Taiwan (BSc). She continued her graduate studies at National Tsing Hua University (MSc) and obtained her PhD degree in Biotechnology from Taiwan International Graduate Program in Academia Sinica and the National Chung Hsing University in 2018. During her PhD study, Dr. Lee became a visiting student at the Technical University of Munich (2016-2018), where she conducted proteomics research on protein modifications and continued her postdoc training from 2018. Since 2021, she leads her own BMBF-funded junior research group at Technical University of Munich.
Dr. Chien-Yun Lee conducts research in the area of mass spectrometry-based clinical proteomics. Her main focus is to develop and apply proteomic technologies to systematically study the unexplored peptidomes and post-translational modifications of proteins in the body fluids of patients affected by disorders of the central nervous system. The goal of her highly collaborative research is to broaden the understanding of disease mechanisms and biomarker discovery to advance medical diagnosis and treatment.
Awards
• BMBF Young Investigator Group, Germany (2021-2026)
• Postdoctoral Research Abroad Program Award, Ministry of Science and Technology, Taiwan (2019-2020)
• TUM University Foundation Fellowship, Germany (2018-2019)
• MOST-DAAD scholarship for PhD candidate, DAAD, Germany (2016-2018)
• Scholarship of Taiwan International Graduate Program, Academia Sinica, Taiwan (2012-2015)
Key Publications (all publications)
Cheung TK, Lee CY, Bayer FP, McCoy A, Kuster B, Rose CM. “Defining the carrier proteome limit for single-cell proteomics”. Nature methods. 2021;18(1):76-83
Abstract*Yang YF, *Lee CY, Hsieh JY, Liu YL, Lin CL, Liu GY, et al. “Regulation of polyamine homeostasis through an antizyme citrullination pathway”. Journal of cellular physiology. 2021;236(8):5646-63.*co-first authors
Abstract*Zecha J, *Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, et al. “Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing”. Molecular & cellular proteomics : MCP. 2020;19(9):1503-22. *co-first authors
AbstractLee CY, Wang D, Wilhelm M, Zolg DP, Schmidt T, Schnatbaum K, et al. “Mining the Human Tissue Proteome for Protein Citrullination”. Molecular & cellular proteomics : MCP. 2018;17(7):1378-91
AbstractLee CY, Lin CC, Liu YL, Liu GY, Liu JH, Hung HC. “Molecular Interplay between the Dimer Interface and the Substrate-Binding Site of Human Peptidylarginine Deiminase 4”. Scientific reports. 2017;7:42662.
Abstract