Dr. Golo Storch

Emmy Noether Research Group/ ERC Starting Grant

“Designed, Flavin-Based Multistate Catalysis”

Organic Chemistry I

Academic Career and Research Areas

After having performed undergraduate and graduate studies in Chemistry at Heidelberg University (2007–2012), Dr. Storch joined the group of Prof. Trapp for his doctorate (2016). During his thesis he worked on the development of stereodynamic ligands and their application in self-amplifying catalysis. Subsequently, he moved to Yale for postdoctoral studies in the laboratory of Prof. Miller (2016–2018) with a focus on quinone redox-interconversion and peptide ligands for site-selective catalysis. Since 2019 he is a research group leader at TUM. 

Dr. Storch (b. 1988) conducts research in the area of site- and stereoselective catalysis. In this context, his work is centered around using flavin-based catalysts that are capable of excelling in a variety of different chemical transformations with non-covalent interactions being key to controlling the catalytically active center. Besides fundamental interest in these new catalytic reactions, catalyst design is performed with the aim for modification of organic compounds of increasing complexity with a focus on peptide natural products. 

Awards

  • Research Award of the Dr. Otto Röhm Memorial Foundation (2023) 
  • Starting Grant 2023 of the European Research Council (2023) 
  • ADUC Prize of the German Chemical Society (2023)
  • Member of the Young College of the Bavarian Academy of Sciences and Humanities (2023)

Rehpenn A, Hindelang S, Truong K.-N., Pöthig A, Storch G: "Enhancing Flavins Photochemical Activity in Hydrogen Atom Abstraction and Triplet Sensitization through Ring-Contraction" Angew. Chem. Int. Ed. 2024; 63: e202318590.

Abstract

Walter A, Eisenreich W, Storch G: "Photochemical Desaturation and Epoxidation with Oxygen by Sequential Flavin Catalysis." Angew. Chem. Int. Ed. 2023; 62: e202310634.

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Rehpenn A, Walter A, Storch G: “Molecular flavin catalysts for C–H functionalisation and derivatisation of dehydroamino acids.” Chem. Sci. 2022; 13: 14151-14156.

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Foja R, Walter A, Jandl C, Thyrhaug E, Hauer J, Storch G: “Reduced Molecular Flavins as Single-Electron Reductants after Photoexcitation.” J. Am. Chem. Soc. 2022; 144: 4721–4726.

Abstract

Walter A, Storch G: „Synthetic C‐6 Aminoflavin Catalysts Enable Aerobic Bromination of Oxidation‐Prone Substrates”. Angew. Chem. Int. Ed. 2020; 59: 22505–22509.

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